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List of Successful Candidates for the FY2025 TeSH GAP Fund Program “STEP1”
TeSH has selected 24 research projects for the FY2025 TeSH GAP Fund Program “STEP1” on the Startup Ecosystem Co-Creation Program for the New Industry Creation Fund for University Startups as follows
Life Science
Kanazawa University
Principal Investigator | Research Theme |
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Associate Professor KURODA, Kosuke | Development of "ZILusion": solvent of hardly soluble drugs |
Drugs that are insoluble in both water and dimethyl sulfoxide are difficult to handle, posing challenges in evaluating their efficacy and administering them. In this research project, we aim to address this issue by enhancing drug solubility using zwitterionic liquids to develop new pharmaceuticals. | |
Assistant Professor ZAIMOKU, Yoshitaka | Implementation of HLA loss detection |
HLA loss in leukemia and aplastic anemia is a mechanism of immune evasion that affects both diagnosis and treatment. We aim to implement our detection technology to provide optimal treatment for patients with hematologic disorders. | |
Professor MATSUMOTO, Kunio | A Breakthrough Biopharmaceutical for Feline Chronic Kidney Disease |
Many cats lose their lives to chronic kidney disease, yet effective treatments remain limited. Building on our research into the HGF-MET pathway, a key regulator of kidney regeneration, we have successfully developed a versatile and safe biopharmaceutical candidate for the treatment of chronic kidney disease. |
University of Toyama
Principal Investigator | Research Theme |
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Associate Professor UTA, Daisuke | Realizing a New Home Treatment Business with Low-Level Laser Therapy Devices |
In order to provide new treatment options for patients worldwide who suffer from itching, we aim to develop and commercialize low-level laser therapy devices that are easy and safe for patients to use at home, reducing the burden of hospital visits and enabling immediate treatment. |
University of Fukui
Principal Investigator | Research Theme |
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Professor FUJITA, Satoshi | Direct Electrospun Hydrogel Nanofiber-based Adhesion Barrier |
We are developing an adhesion barrier with hemostatic effects, composed of hydrogel nanofibers that can be directly electrospun onto the affected area during surgery, along with a clinical-grade spray device for its application. |
Komatsu University
Principal Investigator | Research Theme |
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Professor HASHIMOTO, Yasunari | Commercialization of Control Technology Using Non-invasive Brain Waves |
In this research project, we aims to commercialize an innovative rehabilitation support technology that integrates a non-invasive, EEG-controlled walking assistance and rehabilitation device with functions for neural recovery assessment and autonomic nervous system monitoring. | |
Professor YAMAOKA, Yoshihisa | Development of photoacoustic imaging system to assess skin properties and diseases |
In this research, we have developed a photoacoustic imaging system integrated with a self-healing Bessel beam. This system enables high-contrast visualization of deep biological tissues, contributing to the prevention and treatment of skin diseases, as well as supporting advancements in beauty and health. |
Technology
Japan Advanced Institute of Science and Technology (JAIST)
Principal Investigator | Research Theme |
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Professor UNOKI, Masashi | Development of deep speech-information hiding/deepfake speech detection methods for speech spoofing countermeasure |
In this research project, we are developing fundamental technologies for deep speech information hiding methods that embed secret information in speech, as well as methods for accurately detecting deepfake speech as a countermeasure against speech spoofing created using AI-based speech synthesis techniques. | |
Associate Professor NISHIMURA, Shun | Business for solid catalyst informatics by parallel reactor system and data analysis platform |
For the catalyst development through the data science approaches (known as Catalyst Informatics), we provide a unique reactor for the effective collection of catalyst performance data, and the data analytical methodologies via the multifunctional CADS platform. | |
Associate Professor UEDA, Jumpei | Realizing the ultimate low-environmental-impact transparent luminescent material with long and bright persistent luminescence and excellent semi-permanent durability |
We have successfully developed transparent ceramics with long persistent luminescence, capable of storing light energy, using a simple method that does not require vacuum sintering. By leveraging the material's outstanding afterglow performance, optical transmittance, and mechanical properties, we aim to create new applications. |
Kanazawa University
Principal Investigator | Research Theme |
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Associate Professor TAKASUGI, Keigo | 100% Japan-Made Dental CAD/CAM Crown Manufacturing System |
We are developing Japan’s first fully domestically-produced dental CAD/CAM crown manufacturing system. By integrating a proprietary spiral tool path generation algorithm with a milling machine specifically engineered for this purpose, our system dramatically reduces processing time. Its compact and lightweight design makes it ideally suited for cost-effective implementation in small-scale dental laboratories. | |
Assistant Professor NISHIMURA, Toshihiro | Business development of 3D printer capable of one-shot printing of force sensors |
This research project aims to commercialize a 3D printer capable of printing force sensors, incorporate temperature compensation, and develop a plantar pressure sensor. We will also participate in exhibitions to understand social needs. |
Toyama Prefectural University
Principal Investigator | Research Theme |
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Professor TOUYAMA, Hideaki | Commercialization of earphone-type EEG device and the analysis system for higher brain functions |
We are developing a user-friendly, compact wireless EEG and collecting and analyzing EEG data from a population for marketing and various engineering applications. We will also conduct market research and interviews with companies to develop and evaluate a minimum viable product. |
Ishikawa Prefectural University
Principal Investigator | Research Theme |
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Associate Professor MATSUZAKI, Chiaki | Commercialization of technology to enhance the functionality of industrial enzymes |
We aim for the practical application of our technology to stabilize enzymes, which are used as catalysts in various industries. The technology is based on rational design using three-dimensional structures and theoretical calculation using a supercomputer. |
Kanazawa Institute of Technology
Principal Investigator | Research Theme |
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Associate Professor FUJITA, Hagino | Development of Elliptical Microwave Heating Chamber |
Microwave heating equipment has a wide range of applications, including the heating, drying, and sterilization of food and industrial materials. This research project has achieved exceptionally high heating efficiency by adopting an elliptical heating chamber. We aim to expand globally by introducing this device to heating equipment manufacturers. |
Environment
Japan Advanced Institute of Science and Technology (JAIST)
Principal Investigator | Research Theme |
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Senior Lecturer HIROSE, Daisuke | An easy-to-use smart food quality check system for everyone, enabled by hybrid technology combining oxide thin-film transistor sensors and AI |
This research project aims to implement an easy-to-use food quality check system by combining oxide thin-film transistor sensors with AI-based detection and analysis technologies. In particular, we are developing a technology that enables anyone to test easily for allergens contained in food. | |
Doctoral Course KATO, Yusuke | Business of freezing and storing pig semen using innovative cryopreservation technology |
We are developing cryoprotectants for freezing and storing pig semen. Our goal is to expand into a business involving the sale of frozen and thawed pig semen. Through this research project, we aim to advance the development to the stage where the cryoprotectants for pig semen can be commercially available. |
Kanazawa University
Principal Investigator | Research Theme |
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Professor TSUJIGUCHI, Takuya | Creating a New Business in Next-Generation Emergency Power Systems with Enhanced Portability and Storability |
This research project aims to establish a business that develops compact power systems using formic acid as a fuel for emergency power supply during disasters. Formic acid is environmentally friendly, as it can be synthesized from waste, CO₂, and renewable energy sources, and offers excellent storability. | |
Associate Professor HIROSE, Daisuke | Commercialization of Innovative Platform Technology for Extremely-efficient Dissolution, Dispersion, Regeneration and transformation of Hardly Soluble Molecules |
We aim to commercialize an innovative catalytic platform technology for extremely-efficient dissolution, dispersion, regeneration, and transformation of hardly soluble materials that are difficult to handle despite their high demand—achieving substantial reductions in time, energy, and resource consumption during processing. | |
Associate Professor MASHIO, Asami | Establishment of methods for recovering precious metals from industrial waste and the hydrosphere |
Japan relies heavily on imports for most valuable metals, making its recycling increasingly important. In this research project, we aim to recover precious metals using adsorbents capable of selectively extracting them from highly acidic or alkaline industrial wastewater and submarine hydrothermal water. |
Toyama Prefectural University
Principal Investigator | Research Theme |
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Lecturer KAMAKURA, Masaki | Innovative challenge to discover the safe low molecular medicines to prevent honeybee death from a specific pathogen mediated by varroa mite. |
Honeybees are essential for pollinating crops. In recent years, they have suffered individual death worldwide due to a specific pathogen mediated by the varroa mite. This is a critical issue in the agricultural sector. In this research project, we aim to discover the safe low molecular medicines to prevent honeybee deaths. |
Fukui Prefectural University
Principal Investigator | Research Theme |
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Professor NORIKI, Sakon | Development and Social Implementation of a Simple Detection Kit for Dermatophytosis (Ringworm) in Pets, Livestock, and Other Animals. |
Dermatophytosis, commonly known as athlete's foot, is a zoonotic fungal infection that affects pets and livestock. We have developed a rapid and simple diagnostic tool, a dermatophyte antigen kit, which we are applying to the diagnosis of dermatophytosis in animals. We aim to obtain approval for the kit as a veterinary diagnostic tool and promote its practical implementation. | |
Professor SUETAKE, Hiroaki | Salinity-Driven Method for Introducing Beneficial Microbiota onto the Skin of Ayu and Rainbow Trout |
Bacterial coldwater disease is a serious infectious disease that causes significant damage to rainbow trout and ayu, yet effective preventive measures are limited. In this research project, we are developing an efficient method to introduce beneficial microbiota onto the skin of fish, particularly rainbow trout, to suppress the growth of the causative pathogen. |
Regional, Others
Kanazawa College of Art
Principal Investigator | Research Theme |
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Professor KUWAMURA, Sawako | KANABI KOGEI+: Expanding into Global Luxury Markets through Cross-Disciplinary KOGEI Innovation |
This research project aims to commercialize an art business targeting luxury markets through the creation of cross-disciplinary, high value-added artworks, in collaboration with 15 technical specialists at the College's KANABI Studio (interdisciplinary workshops), who also work as artists. |